We have published a new Application Note 025 on the simple and efficient correction of solvent effects in SPR. Label-Enhanced SPR is immune to bulk refractive index variations, so even very large variations in sample solvent composition can be tolerated.
This is especially beneficial when analysing small molecules or fragments in solutions with varying DMSO content. However, the same technique can be used to treat bulk disturbances in general, e.g., the occurrence of varying glycerol concentrations in antibody preparations.
For a copy of the new Application Note 025, or for any other enquiries, please contact us at firstname.lastname@example.org.