Episentum will present a poster at the Advances in Drug Discovery meeting, Cambridge, UK, 6-7 March 2017. The poster will demonstrate how Label-Enhanced SPR can improve the surface plasmon resonance analysis of small molecules as well as larger biomolecules.
We’re looking forward to meeting with lots of SPR users, including old and new customers. For any information on LE-SPR prior to the meeting, or to book a one-to-one meeting, please contact us at info@episentum.com.
To celebrate the approaching Holiday Season, we’re offering free licenses to our Label-Enhanced SPR software. We want to help more scientists get started with LE-SPR, and we also want to reward our existing customers. So here’s the offer:
For any enquiries, please contact us at sales@episentum.com.
We have published a new Application Note 025 on the simple and efficient correction of solvent effects in SPR. Label-Enhanced SPR is immune to bulk refractive index variations, so even very large variations in sample solvent composition can be tolerated.
This is especially beneficial when analysing small molecules or fragments in solutions with varying DMSO content. However, the same technique can be used to treat bulk disturbances in general, e.g., the occurrence of varying glycerol concentrations in antibody preparations.
For a copy of the new Application Note 025, or for any other enquiries, please contact us at sales@episentum.com.
Episentec, the company that developed the pioneering Label-Enhanced SPR technology, is now evolving into Episentum. We do this change to highlight the extension of our product range.
Episentum still offers the same high-performance Episentec™ reagents and EpiGrammer™ software for Label-Enhanced SPR, and the same high level of technical support on the implementation of the technology.
We will continue developing and offering products that improve the performance of biosensor instruments, and we’re looking forward to continue serving our customers – old as well as new. For any enquiries, please contact us at sales@episentum.com.
Through our collaboration with Biosensor Applications AB, a leader in the development of mobile equipment for drugs and explosives detection, we are now able to offer highly specific, monoclonal antibodies against drugs of abuse. All antibodies are extensively purified using state-of-the art methodology, carefully quality controlled, and functionally characterized using QCM (quartz crystal microbalance) and SAW (surface acoustic wave) biosensors. Recommended applications are biosensors, optical as well as gravimetric, ELISA, and similar applications requiring high quality, primary antibodies.
Please check out our Monoclonal Antibodies page for more info. For any enquiries and orders regarding antibodies, please contact us at: sales@episentum.com.
To celebrate the approaching end of year 2015, we are offering the following discounts on any orders on our range of Label-Enhanced SPR products placed before the end of the year:
For any additional information, for a quotation, or to place an order, please contact sales@episentum.com.
Download pdf here: Episentec December 2015
We have published four new Technical Notes, i.e. simple guides on the practical implementation of Label-Enhanced SPR. Please check out our Technical Notes page for a complete list of available TechNotes, and please contact sales@episentum.com for a copy of any of the TechNotes.
The new TechNotes are:
Technical Note 007: A Biacore™ MDL method template for inhibition-in-solution (ISA) assays
Technical Note 008: A Biacore™ MDL method template for kinetic assays
These two TechNotes contain ready-to-use methods for customers running MDL methods on e.g. Biacore™ 2000 and Biacore™ 3000. The templates can be used right off, or modified according to the user’s requirements.
Technical Note 009: EpiGrammer™ Tutorial 1: Basic case
Technical Note 010: EpiGrammer™ Tutorial 2: Dual-colour case (two binding species)
These two TechNotes contain simple step-by-step instructions on the use of EpiGrammer™ software. TechNote 009 covers the most basic case, while TechNote 010 covers the case with two simultaneously binding species described in our Application Note 024.
Surface Plasmon Resonance is usually regarded as an indiscriminate biosensing technique that monitors the binding of any molecule to the sensor surface, without being able to determine the identity of the binding species. However, using Label-Enhanced SPR, it is possible to discriminate and quantify the binding of two species – one dye-labelled and one unlabelled – simultaneously, even on standard single-wavelength SPR instruments. This feature is very valuable, for example, when studying complex biochemical binding mechanisms, such as competing reactions or allosteric effects. In our new Application Note 024 we present an example on a Biacore™ SPR instrument: the resolution of a mixed, two-species sensorgram into two separate sensorgrams for the two components.
For a copy of the new Application Note 024, or for any other enquiries, please contact sales@episentum.com .
We will complete our European Biacore™ User Meeting roundtrip by presenting the Label-Enhanced SPR concept at the Biacore User Meeting in Berlin, Germany, 1-2 October 2015. Looking forward to networking with many Biacore users and to discussing Label-Enhanced SPR applied to small molecules as well as proteins. For any information prior to the meeting, please contact us at sales@episentum.com.
Episentec will present the Label-Enhanced SPR concept at the Biacore™ User Meeting at Stansted Airport, UK, 23-24 September 2015. Looking forward to meeting many British Biacore users and to discussing Label-Enhanced SPR applied to small molecules as well as proteins. For any information prior to the meeting, please contact us at sales@episentum.com.